논문 썸네일형 리스트형 Robust enumeration of cell subsets from tissue expression profiles Robust enumeration of cell subsets from tissue expression profiles We introduce CIBERSORT, a method for characterizing cell composition of complex tissues from their gene expression profiles. When applied to enumeration of hematopoietic subsets in RNA mixtures from fresh, frozen and fixed tissues, including solid tumors, CIBERSORT outperformed other methods with respect to noise, unknown mixture.. 더보기 논읽남 1. Proteogenomic integration reveals therapeutic targets in breast cancer xenografts 보호되어 있는 글입니다. 더보기 pharmacogenomics alternative drug sensitivity metrics improve preclinical cancer pharmacogenomicsGR50 (Growth rate inhibition 50) : A measure of potency. it is the concentration of drug that reduces cell proliferation rate by one-halfGRmax : A measure of efficacy. it is the maximum effect of a drug at the highest tested concentrationGRaoc : Combines both in an integrated 'area over the curve' value Integrative C.. 더보기 Batch effect 배치 효과 없애는 방법론 Methods that remove batch effects while retaining group differences may lead to exaggerated confidence in downstream analyseshttps://academic.oup.com/biostatistics/article/17/1/29/1744261/Methods-that-remove-batch-effects-while-retaining SVA package https://www.bioconductor.org/packages/devel/bioc/vignettes/sva/inst/doc/sva.pdfhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3307112/ 더보기 Computing in Biotechnology: Omics and Beyond http://www.cell.com/trends/biotechnology/fulltext/S0167-7799(17)30060-4 더보기 이전 1 2 다음