Pharos: Target list DB

 

https://pharos.nih.gov/

Pharos: Illuminating the Druggable Genome

Pharos is the user interface to the Knowledge Management Center (KMC) for the Illuminating the Druggable Genome (IDG) program funded by the National Institutes of Health (NIH) Common Fund. (Grant No. 1U24CA224370-01). The goal of KMC is to develop a comprehensive, integrated knowledge-base for the Druggable Genome (DG) to illuminate the uncharacterized and/or poorly annotated portion of the DG, focusing on three of the most commonly drug-targeted protein families:

• G-protein-coupled receptors (GPCRs)
• Ion channels (ICs)
• Kinases

The Pharos interface provides facile access to most data types collected by the KMC. Given the complexity of the data surrounding any target, efficient and intuitive visualization has been a high priority, to enable users to quickly navigate & summarize search results and rapidly identify patterns. A critical feature of the interface is the ability to perform flexible search and subsequent drill down of search results. Underlying the interface is a GraphQL API that provides programmatic access to all KMC data, allowing for easy consumption in user applications.

 

클릭클릭으로 쉽게 모든 유전자들에 대해 binding하는 유전자 리스트나 targetable여부 등을 쉽게 제공해준다.

앞으로 onco-target을 찾을 때 도움이 될 것으로 예상됨.